Real-time genomics for One Health

Urban, Lara, Perlas, Albert, Francino, Olga, Martí-Carreras, Joan, Muga, Brenda A., Mwangi, Jenniffer W., Boykin Okalebo, Laura, Stanton, Jo Ann L., Black, Amanda, Waipara, Nick, Fontsere, Claudia, Eccles, David, Urel, Harika, Reska, Tim, Morales, Hernán E., Palmada-Flores, Marc, Marques-Bonet, Tomas, Watsa, Mrinalini, Libke, Zane, Erkenswick, Gideon and van Oosterhout, Cock ORCID: (2023) Real-time genomics for One Health. Molecular Systems Biology, 19 (8). ISSN 1744-4292

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The ongoing degradation of natural systems and other environmental changes has put our society at a crossroad with respect to our future relationship with our planet. While the concept of One Health describes how human health is inextricably linked with environmental health, many of these complex interdependencies are still not well-understood. Here, we describe how the advent of real-time genomic analyses can benefit One Health and how it can enable timely, in-depth ecosystem health assessments. We introduce nanopore sequencing as the only disruptive technology that currently allows for real-time genomic analyses and that is already being used worldwide to improve the accessibility and versatility of genomic sequencing. We showcase real-time genomic studies on zoonotic disease, food security, environmental microbiome, emerging pathogens, and their antimicrobial resistances, and on environmental health itself – from genomic resource creation for wildlife conservation to the monitoring of biodiversity, invasive species, and wildlife trafficking. We stress why equitable access to real-time genomics in the context of One Health will be paramount and discuss related practical, legal, and ethical limitations.

Item Type: Article
Additional Information: © 2023 The Authors. Published under the terms of the CC BY 4.0 license.
Uncontrolled Keywords: global health,nanopore sequencing,nature conservation,one health,real-time genomics,information systems,biochemistry, genetics and molecular biology(all),immunology and microbiology(all),agricultural and biological sciences(all),computational theory and mathematics,applied mathematics,sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/1700/1710
Faculty \ School: Faculty of Science > School of Environmental Sciences
UEA Research Groups: Faculty of Science > Research Centres > Centre for Ecology, Evolution and Conservation
Related URLs:
Depositing User: LivePure Connector
Date Deposited: 21 Jul 2023 13:30
Last Modified: 11 Aug 2023 10:30
DOI: 10.15252/msb.202311686


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