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Martin, Claire A., Matthews, Gareth D.K. 
ORCID: https://orcid.org/0000-0001-8353-4806 and Huang, Christopher L.H.
(2012)
Sudden cardiac death and inherited channelopathy:The basic electrophysiology of the myocyte and myocardium in ion channel disease.
Heart, 98 (7).
pp. 536-543.
ISSN 1355-6037
Abstract
Mutations involving cardiac ion channels result in abnormal action potential formation or propagation, leading to cardiac arrhythmias. Despite the large impact on society of sudden cardiac death resulting from such arrhythmias, understanding of the underlying cellular mechanism is poor and clinical risk stratification and treatment consequently limited. Basic research using molecular techniques, as well as animal models, has proved extremely useful in improving our knowledge of inherited arrhythmogenic syndromes. This offers the practitioner tools to accurately diagnose rare disorders and provides novel markers for risk assessment and a basis for new strategies of treatment.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | cardiology and cardiovascular medicine ,/dk/atira/pure/subjectarea/asjc/2700/2705 |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 10 Nov 2022 13:31 |
| Last Modified: | 10 Nov 2022 13:31 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/89774 |
| DOI: | 10.1136/heartjnl-2011-300953 |
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