Mateo-Estrada, Valeria, Vali, Leila, Hamouda, Ahmed, Evans, Benjamin A. ORCID: https://orcid.org/0000-0001-6849-9758 and Castillo-Ramirez, Santiago (2022) Acinetobacter baumannii sampled from cattle and pigs represent novel clones. Microbiology Spectrum, 10 (4). ISSN 2165-0497
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Abstract
Acinetobacter baumannii is a very important human pathogen. Nonetheless, we know very little about nonhuman isolates of A. baumannii. Here, we determine the genomic identity of 15 Scottish cattle and pig isolates, as well as their antibiotic and virulence genetic determinants, and compare them with 148 genomes from the main human clinical international clones. Our results demonstrate that cattle and pig isolates represent novel clones well separated from the major international clones. Furthermore, these new clones showed fewer antibiotic resistance genes and may have fewer virulence genes than human clinical isolates.
Item Type: | Article |
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Additional Information: | Funding information: This work was supported by CONACyT Ciencia Básica 2016 (grant no. 284276) and “Programa de Apoyo a Proyectos de Investigación e Innovación Tecnológica PAPIIT” (grant no. IN206019) given to S.C.-R. V.M.-E. is a doctoral student from the Programa de Doctorado en Ciencias Biomédicas, Universidad Nacional Autónoma de México, and she is funded by a CONACYT doctoral fellowship (no. 1005234). |
Uncontrolled Keywords: | acinetobacter baumannii,one health,animal isolates,antibiotic resistance,bacterial clones,genome epidemiology,physiology,ecology,immunology and microbiology(all),genetics,microbiology (medical),cell biology,infectious diseases ,/dk/atira/pure/subjectarea/asjc/1300/1314 |
Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health Faculty of Medicine and Health Sciences > Research Groups > Pathogen Biology Group |
Related URLs: | |
Depositing User: | LivePure Connector |
Date Deposited: | 13 Jun 2022 14:30 |
Last Modified: | 23 Oct 2024 23:59 |
URI: | https://ueaeprints.uea.ac.uk/id/eprint/85568 |
DOI: | 10.1128/spectrum.01289-22 |
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