Tools
Tools
Hou In Chou, Oscar, Zhou, Jiandong, Lee, Teddy Tai Loy, Kot, Thompson, Lee, Sharen, Ka Chung Wai, Abraham, Wong, Wing Tak, Zhang, Qingpeng, Han Cheng, Shuk, Liu, Tong, Vassiliou, Vassilios S. 
ORCID: https://orcid.org/0000-0002-4005-7752, Man Yung Cheung, Bernard and Tse, Gary
(2022)
Comparisons of the risk of myopericarditis between COVID-19 patients and individuals receiving COVID-19 vaccines: a population-based study.
Clinical Research in Cardiology, 111 (10).
1098–1103.
ISSN 1861-0684
Preview |
PDF (Published_Version)
- Published Version
Available under License Creative Commons Attribution. Download (877kB) | Preview |
Abstract
Background: Both COVID-19 infection and COVID-19 vaccines have been associated with the development of myopericarditis. The objective of this study is to (1) analyse the rates of myopericarditis after COVID-19 infection and COVID-19 vaccination in Hong Kong, (2) compared to the background rates, and (3) compare the rates of myopericarditis after COVID-19 vaccination to those reported in other countries. Methods: This was a population-based cohort study from Hong Kong, China. Patients with positive RT-PCR test for COVID-19 between 1st January 2020 and 30th June 2021 or individuals who received COVID-19 vaccination until 31st August were included. The main exposures were COVID-19 positivity or COVID-19 vaccination. The primary outcome was myopericarditis. Results: This study included 11,441 COVID-19 patients from Hong Kong, four of whom suffered from myopericarditis (rate per million: 326; 95% confidence interval [CI] 127–838). The rate was higher than the pre-COVID-19 background rate in 2019 (rate per million: 5.5, 95% CI 4.1–7.4) with a rate ratio of 55.0 (95% CI 21.4–141). Compared to the background rate, the rate of myopericarditis among vaccinated subjects in Hong Kong was similar (rate per million: 5.5; 95% CI 4.1–7.4) with a rate ratio of 0.93 (95% CI 0.69–1.26). The rates of myocarditis after vaccination in Hong Kong were comparable to those vaccinated in the United States, Israel, and the United Kingdom. Conclusions: COVID-19 infection was associated with significantly higher rate of myopericarditis compared to the vaccine-associated myopericarditis.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | covid-19,myocarditis,myopericarditis,pericarditis,vaccine,cardiology and cardiovascular medicine,sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/2700/2705 |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health Faculty of Science > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 03 Mar 2022 14:30 |
| Last Modified: | 19 Oct 2023 03:17 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/83875 |
| DOI: | 10.1007/s00392-022-02007-0 |
Downloads
Downloads per month over past year
Actions (login required)
 |
View Item |