Application of a numerical index of discriminatory power to a comparison of four physiochemical typing methods for Candida albicans

Hunter, P. R. ORCID: https://orcid.org/0000-0002-5608-6144 and Fraser, C. A. (1989) Application of a numerical index of discriminatory power to a comparison of four physiochemical typing methods for Candida albicans. Journal of Clinical Microbiology, 27 (10). pp. 2156-2160. ISSN 0095-1137

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Abstract

Four typing methods for the strain differentiation of Candida albicans (morphotyping, resistotyping, extracellular enzyme production, and carbon source assimilation reactions) were compared on a single population of 100 strains. An index of discriminatory power was used to facilitate this comparison. Extracellular enzyme production had poor discriminatory power, and carbon source assimilation reactions were poorly reproducible. Morphotyping and resistotyping had acceptable reproducibility and discrimination. The use of resistotyping and morphotyping in parallel enhanced discrimination without an unacceptable decrease in reproducibility, although other combinations did not enhance discrimination because reproductibility was impaired.

Item Type:	Article
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023) Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health Faculty of Social Sciences > Research Centres > Water Security Research Centre Faculty of Medicine and Health Sciences > Research Centres > Population Health
Related URLs:	http://www.scopus.com/inward/record.url?...
Depositing User:	LivePure Connector
Date Deposited:	02 Mar 2022 10:30
Last Modified:	19 Oct 2023 03:16
URI:	https://ueaeprints.uea.ac.uk/id/eprint/83834
DOI:	10.1128/jcm.27.10.2156-2160.1989

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