Comparison of image acquisition techniques in four-dimensional flow cardiovascular MR on 3 tesla in volunteers and Tetralogy of Fallot patients

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Zhang, Jun-Mei, Tan, Ju Le, Westenberg, Jos J. M., Zhong, Liang, Tan, Ru San, Zhang, Shuo, Van Der Geest, Rob, Garg, Pankaj ORCID: https://orcid.org/0000-0002-5483-169X, Leong, Bao Ru, Bryant, Jennifer, Tangcharoen, Tarinee and Zhao, Xiaodan (2018) Comparison of image acquisition techniques in four-dimensional flow cardiovascular MR on 3 tesla in volunteers and Tetralogy of Fallot patients. In: 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) 2018, 2018-07-18 - 2018-07-21.

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Abstract

Four-dimensional phase-contrast (PC) velocity-encoded flow magnetic resonance imaging (4D flow MRI) is a potentially valuable tool for studying cardiovascular hemodynamics for disease monitoring and/or treatment planning. In this study we compared the performance of two 4D flow MRI pulse sequences - echo-planar imaging (EPI) and segmented gradient-echo (turbo-field-echo or TFE on vendor's platform) - on a clinical 3T system in 6 human subjects including 3 patients with Tetralogy of Fallot (TOF). For aortic flow rate, the coefficients of variation (COV) between 2D and 4D EPI were 7.0% and 7.7% for controls and patients respectively. The corresponding COV between 2D and 4D TFE were 19.0% and 18.3% for controls and patients respectively. The COV between 4D TFE and 4D EPI were larger than 18.7% in kinetic energy analysis. 4D EPI demonstrated acceptable accuracy of intra-cardiac flow quantification, which was also shown in the ex-vivo phantom measurements.

Item Type: Conference or Workshop Item (Paper)
Uncontrolled Keywords: sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health
Depositing User: LivePure Connector
Date Deposited: 22 Dec 2021 09:30
Last Modified: 31 Jan 2024 03:34
URI: https://ueaeprints.uea.ac.uk/id/eprint/82793
DOI: 10.1109/EMBC.2018.8512412

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