Comparison of image acquisition techniques in four-dimensional flow cardiovascular MR on 3 tesla in volunteers and Tetralogy of Fallot patients

Zhang, Jun-Mei, Tan, Ju Le, Westenberg, Jos J. M., Zhong, Liang, Tan, Ru San, Zhang, Shuo, Van Der Geest, Rob, Garg, Pankaj, Leong, Bao Ru, Bryant, Jennifer, Tangcharoen, Tarinee and Zhao, Xiaodan (2018) Comparison of image acquisition techniques in four-dimensional flow cardiovascular MR on 3 tesla in volunteers and Tetralogy of Fallot patients. In: 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) 2018, 2018-07-18 - 2018-07-21.

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Abstract

Four-dimensional phase-contrast (PC) velocity-encoded flow magnetic resonance imaging (4D flow MRI) is a potentially valuable tool for studying cardiovascular hemodynamics for disease monitoring and/or treatment planning. In this study we compared the performance of two 4D flow MRI pulse sequences - echo-planar imaging (EPI) and segmented gradient-echo (turbo-field-echo or TFE on vendor's platform) - on a clinical 3T system in 6 human subjects including 3 patients with Tetralogy of Fallot (TOF). For aortic flow rate, the coefficients of variation (COV) between 2D and 4D EPI were 7.0% and 7.7% for controls and patients respectively. The corresponding COV between 2D and 4D TFE were 19.0% and 18.3% for controls and patients respectively. The COV between 4D TFE and 4D EPI were larger than 18.7% in kinetic energy analysis. 4D EPI demonstrated acceptable accuracy of intra-cardiac flow quantification, which was also shown in the ex-vivo phantom measurements.

Item Type:	Conference or Workshop Item (Paper)
Uncontrolled Keywords:	sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health
Depositing User:	LivePure Connector
Date Deposited:	22 Dec 2021 09:30
Last Modified:	06 Feb 2025 01:19
URI:	https://ueaeprints.uea.ac.uk/id/eprint/82793
DOI:	10.1109/EMBC.2018.8512412

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