Aggressive cardiac involvement in systemic lupus erythematosus: A case report and a comprehensive literature review

Ashrafi, Reza, Garg, Pankaj ORCID: https://orcid.org/0000-0002-5483-169X, McKay, Ewan, Gosney, John, Chuah, Som and Davis, Gershan (2011) Aggressive cardiac involvement in systemic lupus erythematosus: A case report and a comprehensive literature review. Cardiology Research and Practice, 2011. ISSN 2090-8016

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Abstract

Background. We present the case of a 35-year-old gentleman who presented with an aggressive cardiomyopathy with normal coronary arteries. He was later diagnosed with systemic lupus-related cardiomyopathy. Methods. We undertook an extensive review of the literature regarding cardiac manifestations of lupus and used over 100 journals to identify the key points in pathology, diagnosis, and treatment. Results. We have shown that cardiac lupus can be rapidly progressive and, unless treated early, can have severe consequences. The predominant pathologies are immune complex and accelerated atherosclerosis drive. Treatment comprised of high-level immunosuppression.

Item Type:	Article
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health
Related URLs:	http://www.hindawi.com/journals/crp/2011...
Depositing User:	LivePure Connector
Date Deposited:	21 Dec 2021 13:31
Last Modified:	19 Oct 2023 03:13
URI:	https://ueaeprints.uea.ac.uk/id/eprint/82772
DOI:	10.4061/2011/578390

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