When more is needed: The utility of the frontotemporal dementia scale in ALS

Hsieh, Sharpley, Lillo, Patricia, Kiernan, Matthew C., Hodges, John R. and Mioshi, Eneida (2013) When more is needed: The utility of the frontotemporal dementia scale in ALS. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 14 (3). pp. 169-171. ISSN 2167-8421

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Abstract

ALS and frontotemporal dementia (FTD) utilize different functional rating scales: the ALSFRS-R assesses physical disability whereas the Frontotemporal Dementia Rating Scale assesses behavioural and functional impairment to produce an index of dementia staging. To better consider the applicability of the FRS in an ALS population, 130 patient-carer dyads were investigated. Scores on the ALSFRS-R and FRS were not significantly correlated (r(s) = 0.12, p > 0.10). Furthermore, patients with mild physical disability may rate as severe on the FRS; conversely, individuals who are severely physically disabled may exhibit very few behavioural symptoms. Measures typically used in ALS studies do not fully encapsulate the range of clinical symptoms, particularly from a behavioural perspective.

Item Type:	Article
Uncontrolled Keywords:	aged,diagnosis,methods,female,diagnosis,humans,male,middle aged,standards,severity of illness index
Faculty \ School:	Faculty of Medicine and Health Sciences > School of Health Sciences
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Centres > Norwich Institute for Healthy Aging Faculty of Medicine and Health Sciences > Research Groups > Dementia & Complexity in Later Life Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
Depositing User:	LivePure Connector
Date Deposited:	09 Jul 2021 12:18
Last Modified:	19 Oct 2023 03:00
URI:	https://ueaeprints.uea.ac.uk/id/eprint/80499
DOI:	10.3109/21678421.2013.764899

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