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ToolsHsieh, S., Hodges, J. R., Leyton, C. E. and Mioshi, E. (2012) Longitudinal changes in primary progressive aphasias: Differences in cognitive and dementia staging measures. Dementia and Geriatric Cognitive Disorders, 34 (2). pp. 135-141. ISSN 1420-8008
Full text not available from this repository. (Request a copy)Abstract
BACKGROUND/AIMS: The longitudinal course of three primary progressive aphasia (PPA) variants was examined using Addenbrooke's Cognitive Examination-Revised (ACE-R) and the Frontotemporal dementia Rating Scale (FRS). METHODS: Cases with two assessments on the ACE-R and FRS were selected. A total of 220 assessments were obtained on 55 patients: 17 Alzheimer's disease (AD) and 38 PPA [17 semantic variant (svPPA), 12 non-fluent/agrammatic (naPPA) and 9 logopenic variant (lvPPA) cases]. RESULTS: The annualized rate of change was greater in all PPA variants in comparison with the AD group on the ACE-R whereas only the svPPA and naPPA groups differed from AD on the FRS. CONCLUSIONS: The longitudinal profile differs across PPA syndromes on cognitive and functional measures. Findings have theoretical implications and are relevant to the care of patients with dementia.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | aged,diagnosis,diagnosis,disease progression,female,humans,longitudinal studies,male,middle aged,neuropsychological tests,diagnosis |
| Faculty \ School: | Faculty of Medicine and Health Sciences > School of Health Sciences |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Centres > Norwich Institute for Healthy Aging Faculty of Medicine and Health Sciences > Research Groups > Dementia & Complexity in Later Life Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health |
| Depositing User: | LivePure Connector |
| Date Deposited: | 09 Jul 2021 07:29 |
| Last Modified: | 19 Oct 2023 03:00 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/80484 |
| DOI: | 10.1159/000342347 |
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