New perspectives on the evolution of within-individual genome variation and germline/soma distinction

Suh, Alexander and Dion-Côté, Anne-Marie (2021) New perspectives on the evolution of within-individual genome variation and germline/soma distinction. Genome Biology and Evolution. ISSN 1759-6653

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Abstract

Genomes can vary significantly even within the same individual. The underlying mechanisms are manifold, ranging from somatic mutation and recombination, development-associated ploidy changes and genetic bottlenecks, over to programmed DNA elimination during germline/soma differentiation. In this perspective piece, we briefly review recent developments in the study of within-individual genome variation in eukaryotes and prokaryotes. We highlight an SMBE 2020 virtual symposium entitled “Within-individual genome variation and germline/soma distinction” and the present Special Section of the same name in Genome Biology and Evolution, together fostering cross-taxon synergies in the field to identify and tackle key open questions in the understanding of within-individual genome variation.

Item Type: Article
Faculty \ School: Faculty of Science > School of Biological Sciences
Related URLs:
Depositing User: LivePure Connector
Date Deposited: 27 May 2021 00:10
Last Modified: 16 Jun 2021 00:19
URI: https://ueaeprints.uea.ac.uk/id/eprint/80139
DOI: 10.1093/gbe/evab095

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