Suh, Alexander ORCID: https://orcid.org/0000-0002-8979-9992 and Dion-Côté, Anne-Marie (2021) New perspectives on the evolution of within-individual genome variation and germline/soma distinction. Genome Biology and Evolution, 13 (6). ISSN 1759-6653
Preview |
PDF (Accepted_Manuscript)
- Accepted Version
Available under License Creative Commons Attribution. Download (537kB) | Preview |
Abstract
Genomes can vary significantly even within the same individual. The underlying mechanisms are manifold, ranging from somatic mutation and recombination, development-associated ploidy changes and genetic bottlenecks, over to programmed DNA elimination during germline/soma differentiation. In this perspective piece, we briefly review recent developments in the study of within-individual genome variation in eukaryotes and prokaryotes. We highlight a Society for Molecular Biology and Evolution 2020 virtual symposium entitled "Within-individual genome variation and germline/soma distinction" and the present Special Section of the same name in Genome Biology and Evolution, together fostering cross-taxon synergies in the field to identify and tackle key open questions in the understanding of within-individual genome variation.
Item Type: | Article |
---|---|
Additional Information: | Funding Information: A.S. was supported by the Swedish Research Council Vetenskapsrådet (2016-05139, 2020-04436) and the Swedish Research Council Formas (2017-01597). A.-M.D.-C. was supported by the National Sciences and Engineering Research Council of Canada (RGPIN-2019-05744). |
Uncontrolled Keywords: | dna elimination,chromatin diminution,germline-restricted chromosome,soma variation,ecology, evolution, behavior and systematics,genetics ,/dk/atira/pure/subjectarea/asjc/1100/1105 |
Faculty \ School: | Faculty of Science > School of Biological Sciences |
Related URLs: | |
Depositing User: | LivePure Connector |
Date Deposited: | 27 May 2021 00:10 |
Last Modified: | 25 Sep 2024 15:36 |
URI: | https://ueaeprints.uea.ac.uk/id/eprint/80139 |
DOI: | 10.1093/gbe/evab095 |
Downloads
Downloads per month over past year
Actions (login required)
View Item |