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Suh, Alexander 
ORCID: https://orcid.org/0000-0002-8979-9992 and Dion-Côté, Anne-Marie
(2021)
New perspectives on the evolution of within-individual genome variation and germline/soma distinction.
Genome Biology and Evolution, 13 (6).
ISSN 1759-6653
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Abstract
Genomes can vary significantly even within the same individual. The underlying mechanisms are manifold, ranging from somatic mutation and recombination, development-associated ploidy changes and genetic bottlenecks, over to programmed DNA elimination during germline/soma differentiation. In this perspective piece, we briefly review recent developments in the study of within-individual genome variation in eukaryotes and prokaryotes. We highlight a Society for Molecular Biology and Evolution 2020 virtual symposium entitled "Within-individual genome variation and germline/soma distinction" and the present Special Section of the same name in Genome Biology and Evolution, together fostering cross-taxon synergies in the field to identify and tackle key open questions in the understanding of within-individual genome variation.
| Item Type: | Article |
|---|---|
| Additional Information: | Funding Information: A.S. was supported by the Swedish Research Council Vetenskapsrådet (2016-05139, 2020-04436) and the Swedish Research Council Formas (2017-01597). A.-M.D.-C. was supported by the National Sciences and Engineering Research Council of Canada (RGPIN-2019-05744). |
| Uncontrolled Keywords: | dna elimination,chromatin diminution,germline-restricted chromosome,soma variation,ecology, evolution, behavior and systematics,genetics ,/dk/atira/pure/subjectarea/asjc/1100/1105 |
| Faculty \ School: | Faculty of Science > School of Biological Sciences |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 27 May 2021 00:10 |
| Last Modified: | 06 Apr 2024 01:01 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/80139 |
| DOI: | 10.1093/gbe/evab095 |
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