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Khunti, Kamlesh, Griffin, Simon, Brennan, Alan, Dallosso, Helen, Davies, Melanie J., Eborall, Helen C., Edwardson, Charlotte L., Gray, Laura J., Hardeman, Wendy 
ORCID: https://orcid.org/0000-0002-6498-9407, Heathcote, Laura, Henson, Joe, Pollard, Daniel, Sharp, Stephen J., Sutton, Stephen, Troughton, Jacqui and Yates, Tom
(2021)
Promoting physical activity in a multi-ethnic population at high risk of diabetes: the 48-month PROPELS randomised controlled trial.
BMC Medicine, 19.
ISSN 1741-7015
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Abstract
Background: Physical activity is associated with a reduced risk of type 2 diabetes and cardiovascular disease but limited evidence exists for the sustained promotion of increased physical activity within diabetes prevention trials. The aim of the study was to investigate the long-term effectiveness of the Walking Away programme, an established group-based behavioural physical activity intervention with pedometer use, when delivered alone or with a supporting mHealth intervention. Methods: Those at risk of diabetes (nondiabetic hyperglycaemia) were recruited from primary care, 2013-2015, and randomized to: 1) Control (information leaflet); 2) Walking Away (WA), a structured group education session followed by annual group-based support; or 3) Walking Away Plus (WAP), comprising WA annual group-based support and an mHealth intervention delivering tailored text messages supported by telephone calls. Follow-up was conducted at 12 and 48 months. The primary outcome was accelerometer measured ambulatory activity (steps/day). Change in primary outcome was analysed using analysis of covariance with adjustment for baseline, randomisation and stratification variables. Results: 1366 individuals were randomized (median age = 61 years, ambulatory activity = 6638 steps/day, women = 49%, ethnic minorities = 28%). Accelerometer data were available for 1017 (74%) individuals at 12 months and 993 (73%) at 48 months. At 12 months, WAP increased their ambulatory activity by 547 (97·5% CI 211, 882) steps/day compared to control and were 1.61 (97·5% CI 1·05, 2·45) times more likely to achieve 150 min/week of moderate-to-vigorous physical activity. Differences were not maintained at 48 months. WA was no different to control at 12 or 48 months. Secondary anthropometric and health outcomes were largely unaltered in both intervention groups apart from small reductions in body weight in WA (~1kg) at 12 and 48-month follow-up. Conclusions: Combining a pragmatic group-based intervention with text messaging and telephone support resulted in modest changes to physical activity at 12 months, but changes were not maintained at 48 months. Study registration: ISRCTN 83465245 (registered on 14/6/2012)
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | diabetes prevention,group-based intervention,non-diabetic hyperglycaemia,pedometer,physical activity,randomised controlled trial,mhealth,medicine(all),sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/2700 |
| Faculty \ School: | Faculty of Medicine and Health Sciences > School of Health Sciences |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Centres > Norwich Institute for Healthy Aging Faculty of Medicine and Health Sciences > Research Groups > Behavioural and Implementation Science Faculty of Medicine and Health Sciences > Research Groups > Health Promotion Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 06 May 2021 00:04 |
| Last Modified: | 19 Oct 2023 02:57 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/79936 |
| DOI: | 10.1186/s12916-021-01997-4 |
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