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Pile, Victoria, Smith, Patrick, Leamy, Mary, Oliver, Abigail, Bennett, Eleanor, Blackwell, Simon E., Meiser-Stedman, Richard 
ORCID: https://orcid.org/0000-0002-0262-623X, Stringer, Dominic, Dunn, Barnaby D., Holmes, Emily A. and Lau, Jennifer Y. F.
(2021)
A feasibility randomised controlled trial of a brief early intervention for adolescent depression that targets emotional mental images and memory specificity (IMAGINE).
Behaviour Research and Therapy, 143.
ISSN 0005-7967
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Abstract
Brief, evidence-based interventions for adolescent depression are urgently required, particularly for school-settings. Cognitive mechanisms research suggests dysfunctional mental imagery and overgeneral memory could be promising targets to improve mood. This feasibility randomised controlled trial with parallel symptomatic groups (n = 56) compared a novel imagery-based cognitive behavioural intervention (ICBI) to non-directive supportive therapy (NDST) in school settings. Blind assessments (of clinical symptoms and cognitive mechanisms) took place pre-intervention, post-intervention and follow-up three months later. The trial aimed to evaluate the feasibility and acceptability of the methodology and interventions, and estimate the likely range of effects of the intervention on self-reported depression. The pre-defined criteria for proceeding to a definitive RCT were met: full recruitment occurred within eleven months; retention was 89%; ICBI acceptability was above satisfactory; and no harm was indicated. Intention-to-treat analysis found large effects in favour of ICBI (relative to NDST) at post-intervention in reducing depressive symptoms (d = −1.34, 95% CI [-1.87, −0.80]) and improving memory specificity (d = 0.79 [0.35, 1.23]), a key cognitive target. The findings suggest that ICBI may not only improve mood but also strengthen abilities associated with imagining and planning the future, critical skills at this life stage. A fully powered evaluation of ICBI is warranted. Trial Registration: https://www.isrctn.com/; ISRCTN85369879.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | adolescence,autobiographical memory,depression,imagery rescripting,memory specificity training,mental imagery,experimental and cognitive psychology,clinical psychology,psychiatry and mental health,sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/3200/3205 |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Mental Health Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 28 Apr 2021 23:47 |
| Last Modified: | 19 Oct 2023 02:57 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/79893 |
| DOI: | 10.1016/j.brat.2021.103876 |
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