The early course and treatment of posttraumatic stress disorder in very young children: Diagnostic prevalence and predictors in hospital-attending children and a randomized controlled proof-of-concept trial of trauma-focused cognitive therapy, for 3-8 year olds

Hitchcock, Caitlin, Goodall, Benjamin, Wright, Isobel M., Boyle, Adrian, Johnston, David, Dunning, Darren, Gillard, Julia, Griffiths, Kirsty, Humphrey, Ayla, McKinnon, Anna, Panesar, Inderpal K., Werner-Seidler, Aliza, Watson, Peter, Smith, Patrick, Meiser-Stedman, Richard ORCID: https://orcid.org/0000-0002-0262-623X and Dalgleish, Tim (2022) The early course and treatment of posttraumatic stress disorder in very young children: Diagnostic prevalence and predictors in hospital-attending children and a randomized controlled proof-of-concept trial of trauma-focused cognitive therapy, for 3-8 year olds. Journal of Child Psychology and Psychiatry, 63 (1). pp. 58-67. ISSN 0021-9630

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Abstract

Background: The introduction of developmentally adapted criteria for posttraumatic stress disorder (PTSD) has improved the identification of ≤6-year-old children with clinical needs. Across two studies, we assess predictors of the development of PTSD in young children (PTSD-YC), including the adult-led acute stress disorder (ASD) diagnosis, and provide proof of principle for cognitive-focused therapy for this age range, with the aim of increasing treatment options for children diagnosed with PTSD-YC. Method: Study 1 (N = 105) assessed ASD and PTSD-YC diagnosis in 3- to 8-year-old children within one month and at around three months following attendance at an emergency room. Study 2 (N = 37) was a preregistered (www.isrctn.com/ISRCTN35018680) randomized controlled early-phase trial comparing CBT-3M, a cognitive-focused intervention, to treatment-as-usual (TAU) delivered within the UK NHS to 3- to 8-year-olds diagnosed with PTSD-YC. Results: In Study 1, the ASD diagnosis failed to identify any young children. In contrast, prevalence of acute PTSD-YC (minus the duration requirement) was 8.6% in the first month post-trauma and 10.1% at 3 months. Length of hospital stay, but no other demographic or trauma-related characteristics, predicted development of later PTSD-YC. Early (within one month) diagnosis of acute PTSD-YC had a positive predictive value of 50% for later PTSD-YC. In Study 2, most children lost their PTSD-YC diagnosis following completion of CBT-3M (84.6%) relative to TAU (6.7%) and CBT-3M was acceptable to recipient families. Effect sizes were also in favor of CBT-3M for secondary outcome measures. Conclusions: The ASD diagnosis is not fit for purpose in this age-group. There was a strong and encouraging signal of putative efficacy for young children treated using a cognitive-focused treatment for PTSD, and a larger trial of CBT-3M is now warranted.

Item Type: Article
Uncontrolled Keywords: posttraumatic stress disorder,cognitive behavioral therapy,randomized control trial,young children,pediatrics, perinatology, and child health,developmental and educational psychology,psychiatry and mental health,sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/2700/2735
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Mental Health
Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
Related URLs:
Depositing User: LivePure Connector
Date Deposited: 27 Apr 2021 23:45
Last Modified: 19 Oct 2023 02:57
URI: https://ueaeprints.uea.ac.uk/id/eprint/79885
DOI: 10.1111/jcpp.13460

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