A comparative genomics multitool for scientific discovery and conservation

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Zoonomia Consortium (2020) A comparative genomics multitool for scientific discovery and conservation. Nature, 587 (7833). pp. 240-245. ISSN 0028-0836

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Abstract

The Zoonomia Project is investigating the genomics of shared and specialized traits in eutherian mammals. Here we provide genome assemblies for 131 species, of which all but 9 are previously uncharacterized, and describe a whole-genome alignment of 240 species of considerable phylogenetic diversity, comprising representatives from more than 80% of mammalian families. We find that regions of reduced genetic diversity are more abundant in species at a high risk of extinction, discern signals of evolutionary selection at high resolution and provide insights from individual reference genomes. By prioritizing phylogenetic diversity and making data available quickly and without restriction, the Zoonomia Project aims to support biological discovery, medical research and the conservation of biodiversity.

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Biological Sciences
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Centres > Norwich Institute for Healthy Aging
Related URLs:	http://www.scopus.com/inward/record.url?... http://www.nature.com/articles/s41586-02...
Depositing User:	LivePure Connector
Date Deposited:	30 Jan 2021 01:11
Last Modified:	20 Apr 2023 19:37
URI:	https://ueaeprints.uea.ac.uk/id/eprint/78330
DOI:	10.1038/s41586-020-2876-6

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