Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China

Cao, Shiyi, Gan, Yong, Wang, Chao, Bachmann, Max O., Wei, Shanbo, Gong, Jie, Huang, Yuchai, Wang, Tiantian, Li, Liqing, Lu, Kai, Jiang, Heng, Gong, Yanhong, Xu, Hongbin, Shen, Xin, Tian, Qingfeng, Lv, Chuanzhu, Song, Fujian, Yin, Xiaoxv and Lu, Zuxun (2020) Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China. Nature Communications, 11. ISSN 2041-1723

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Abstract

Stringent COVID-19 control measures were imposed in Wuhan between January 23 and April 8, 2020. Estimates of the prevalence of infection following the release of restrictions could inform post-lockdown pandemic management. Here, we describe a city-wide SARS-CoV-2 nucleic acid screening programme between May 14 and June 1, 2020 in Wuhan. All city residents aged six years or older were eligible and 9,899,828 (92.9%) participated. No new symptomatic cases and 300 asymptomatic cases (detection rate 0.303/10,000, 95% CI 0.270–0.339/10,000) were identified. There were no positive tests amongst 1,174 close contacts of asymptomatic cases. 107 of 34,424 previously recovered COVID-19 patients tested positive again (re-positive rate 0.31%, 95% CI 0.423–0.574%). The prevalence of SARS-CoV-2 infection in Wuhan was therefore very low five to eight weeks after the end of lockdown.

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: LivePure Connector
Date Deposited: 23 Nov 2020 00:52
Last Modified: 16 Sep 2021 11:06
URI: https://ueaeprints.uea.ac.uk/id/eprint/77765
DOI: 10.1038/s41467-020-19802-w

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