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Cao, Shiyi, Gan, Yong, Wang, Chao, Bachmann, Max O. 
ORCID: https://orcid.org/0000-0003-1770-3506, Wei, Shanbo, Gong, Jie, Huang, Yuchai, Wang, Tiantian, Li, Liqing, Lu, Kai, Jiang, Heng, Gong, Yanhong, Xu, Hongbin, Shen, Xin, Tian, Qingfeng, Lv, Chuanzhu, Song, Fujian, Yin, Xiaoxv and Lu, Zuxun
(2020)
Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China.
Nature Communications, 11.
ISSN 2041-1723
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Abstract
Stringent COVID-19 control measures were imposed in Wuhan between January 23 and April 8, 2020. Estimates of the prevalence of infection following the release of restrictions could inform post-lockdown pandemic management. Here, we describe a city-wide SARS-CoV-2 nucleic acid screening programme between May 14 and June 1, 2020 in Wuhan. All city residents aged six years or older were eligible and 9,899,828 (92.9%) participated. No new symptomatic cases and 300 asymptomatic cases (detection rate 0.303/10,000, 95% CI 0.270–0.339/10,000) were identified. There were no positive tests amongst 1,174 close contacts of asymptomatic cases. 107 of 34,424 previously recovered COVID-19 patients tested positive again (re-positive rate 0.31%, 95% CI 0.423–0.574%). The prevalence of SARS-CoV-2 infection in Wuhan was therefore very low five to eight weeks after the end of lockdown.
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