Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China

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Cao, Shiyi, Gan, Yong, Wang, Chao, Bachmann, Max O., Wei, Shanbo, Gong, Jie, Huang, Yuchai, Wang, Tiantian, Li, Liqing, Lu, Kai, Jiang, Heng, Gong, Yanhong, Xu, Hongbin, Shen, Xin, Tian, Qingfeng, Lv, Chuanzhu, Song, Fujian, Yin, Xiaoxv and Lu, Zuxun (2020) Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China. Nature Communications, 11. ISSN 2041-1723

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Official URL: https://www.nature.com/articles/s41467-020-19802-w

Abstract

Stringent COVID-19 control measures were imposed in Wuhan between January 23 and April 8, 2020. Estimates of the prevalence of infection following the release of restrictions could inform post-lockdown pandemic management. Here, we describe a city-wide SARS-CoV-2 nucleic acid screening programme between May 14 and June 1, 2020 in Wuhan. All city residents aged six years or older were eligible and 9,899,828 (92.9%) participated. No new symptomatic cases and 300 asymptomatic cases (detection rate 0.303/10,000, 95% CI 0.270–0.339/10,000) were identified. There were no positive tests amongst 1,174 close contacts of asymptomatic cases. 107 of 34,424 previously recovered COVID-19 patients tested positive again (re-positive rate 0.31%, 95% CI 0.423–0.574%). The prevalence of SARS-CoV-2 infection in Wuhan was therefore very low five to eight weeks after the end of lockdown.

Item Type:	Article
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Centres > Norwich Institute for Healthy Aging Faculty of Medicine and Health Sciences > Research Groups > Health Services and Primary Care Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023) Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health Faculty of Science > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Centres > Population Health
Related URLs:	http://www.scopus.com/inward/record.url?...
Depositing User:	LivePure Connector
Date Deposited:	23 Nov 2020 00:52
Last Modified:	06 Feb 2025 09:31
URI:	https://ueaeprints.uea.ac.uk/id/eprint/77765
DOI:	10.1038/s41467-020-19802-w

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