Spanish adaptation of the Dimensional Apathy Scale (DAS) in amyotrophic lateral sclerosis

Salas, Teresa, Radakovic, Ratko, Rodriguez-Castillo, Víctor, Marín, Saúl, Chaverri, Delia and Rodriguez-Santos, Francisco (2020) Spanish adaptation of the Dimensional Apathy Scale (DAS) in amyotrophic lateral sclerosis. Frontiers in Neurology, 11. ISSN 1664-2295

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Abstract

Aim: To adapt, translate, and utilize the Dimensional Apathy Scale (DAS) in Amyotrophic Lateral Sclerosis (ALS) to the Spanish population. Method: We recruited 104 ALS patients (67 of their caregivers) and 49 controls. Participants completed the Spanish-translated DAS, Geriatric Depression Scale- Short form. Patients were also administered the ALS Functional Rating Scale-Revised (ALSFRS-R). Caregivers additionally completed the informant/caregiver-rated Spanish-translated DAS. The DAS was translated to Spanish using a back-translation method. Test-retest and internal consistency reliability were examined. Divergent validity was assessed by comparing the DAS with the depression scale (GDS-15). Principal Component Analysis (PCA) was applied to explore the substructure of the Spanish DAS. Results: The internal consistency reliability of self-rated Spanish DAS was 0.72 and of the informant/caregiver-rated Spanish DAS was 0.84. Correlations between self-rated DAS subscales and GDS-15 were not statistically significant, with a good test-retest reliability. PCA analysis showed a similar substructure to the original DAS. ALS patients had significantly higher Initiation apathy than controls. Additionally, ALS patient informant/caregiver-rated DAS Emotional apathy was significantly higher than the self-rated, with no significant differences observed in the Executive and Initiation subscales. No association was found between DAS and functional impairment using the ALS Functional Rating Scale (ALSFRS-R). Conclusion: The Spanish translation of the DAS is valid and reliable for use in assessing multidimensional apathy in the Spanish population. Availability of the Spanish DAS will allow for future research to explore different apathy subtypes and their impact in ALS and other conditions.

Item Type:	Article
Additional Information:	Data Availability Statement: The datasets generated for this study are available on request to the corresponding author. Funding information: This study was sponsored by the Spanish Foundation for the promotion of research into Amyotrophic Lateral Sclerosis (FUNDELA). RR was funded by Motor Neurone Disease Scotland and the Motor Neurone Disease Association.
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User:	LivePure Connector
Date Deposited:	03 Nov 2020 11:49
Last Modified:	22 Nov 2024 01:32
URI:	https://ueaeprints.uea.ac.uk/id/eprint/77519
DOI:	10.3389/fneur.2020.562837

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