Left ventricular blood flow kinetic energy assessment by 4D flow cardiovascular magnetic resonance: A systematic review of the clinical relevance

Kaur, Harjinder, Assadi, Hosamadin ORCID: https://orcid.org/0000-0002-6143-8095, Alabed, Samer, Cameron, Donnie ORCID: https://orcid.org/0000-0001-9841-6909, Vassiliou, Vassilios S. ORCID: https://orcid.org/0000-0002-4005-7752, Westenberg, Jos J. M., van der Geest, Rob, Zhong, Liang, Dastidar, Amardeep, Swift, Andrew J. and Garg, Pankaj ORCID: https://orcid.org/0000-0002-5483-169X (2020) Left ventricular blood flow kinetic energy assessment by 4D flow cardiovascular magnetic resonance: A systematic review of the clinical relevance. Journal of Cardiovascular Development and Disease, 7 (3). ISSN 2308-3425

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Abstract

There is an emerging body of evidence that supports the potential clinical value of left ventricular (LV) intracavity blood flow kinetic energy (KE) assessment using four-dimensional flow cardiovascular magnetic resonance imaging (4D flow CMR). The aim of this systematic review is to summarize studies evaluating LV intracavity blood flow KE quantification methods and its potential clinical significance. Methods: A systematic review search was carried out on Medline, Pubmed, EMBASE and CINAHL. Results: Of the 677 articles screened, 16 studies met eligibility. These included six (37%) studies on LV diastolic function, another six (37%) studies on heart failure or cardiomyopathies, three (19%) studies on ischemic heart disease or myocardial infarction and finally, one (6%) study on valvular heart disease, namely, mitral regurgitation. One of the main strengths identified by these studies is high reproducibility of LV blood flow KE hemodynamic assessment (mean coefficient of variability = 6 ±  2%) for the evaluation of LV diastolic function. Conclusions: The evidence gathered in this systematic review suggests that LV blood flow KE has great promise for LV hemodynamic assessment. Studies showed increased diagnostic confidence at no cost of additional time. Results were highly reproducible with low intraobserver variability.

Item Type:	Article
Additional Information:	Funding information: This work was supported by the Wellcome Trust (AS: 205,188/Z/16/Z) and National Medical Research Council Singapore (LZ: NMRC/OFIRG/0018/2016; MOH-000,351). PG is supported by Academy of Sciences Starter Grant (PG: SGL018\1100).
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health Faculty of Science > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Centres > Population Health Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health
Depositing User:	LivePure Connector
Date Deposited:	10 Sep 2020 00:07
Last Modified:	19 Oct 2023 02:46
URI:	https://ueaeprints.uea.ac.uk/id/eprint/76809
DOI:	10.3390/jcdd7030037

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