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Tung, Iong Man, Barlas, Raphae S., Vart, Priya, Bettencourt-Silva, Joao H., Clark, Allan B. 
ORCID: https://orcid.org/0000-0003-2965-8941, Sawanyawisuth, Kittisak, Kongbunkiat, Kannikar, Kasemsap, Narongrit, Tiamkao, Somsak and Myint, Phyo K.
(2021)
Association of chronic kidney disease with outcomes in acute stroke.
Acta Neurologica Belgica, 121 (5).
1241–1246.
ISSN 0300-9009
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Abstract
Previous studies have found an association between chronic kidney disease and poor outcomes in stroke patients. However, there is a paucity of literature evaluating this association by stroke type. We therefore aimed to explore the association between CKD and stroke outcomes according to type of stroke. The data consisting of 594,681 stroke patients were acquired from Universal Coverage Health Security Insurance Scheme Database in Thailand. Binary logistic regression was used to assess the relationship of CKD and outcomes, which were as follows; in-hospital mortality, long length of stay (>3 days), pneumonia, sepsis, respiratory failure and myocardial infarction. Results: after fully adjusting for covariates, CKD was associated with increased odds of in-hospital mortality in patients with ischemic (OR 1.32; 95% CI = 1.27–1.38), haemorrhagic (OR 1.31; 95% CI = 1.24–1.39), and other undetermined stroke type (OR 1.44; 95% CI = 1.21–1.73). CKD was found to be associated with increased odds of pneumonia, sepsis, respiratory failure and myocardial infarction in ischaemic stroke. While CKD was found to be associated with increase odds of sepsis, respiratory failure, and myocardial infarction, decrease odds of pneumonia was observed in patients with haemorrhagic stroke. In other undetermined stroke type, CKD was found to only be associated with increase odds of sepsis and respiratory failure, while there is no significant association of CKD and increase or decrease odds with pneumonia and myocardial infarction. CKD was associated with poor outcomes in all stroke types. CKD should be considered as part of stroke prognosis as well as identifying at risk patient population for in-hospital complications.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | chronic kidney disease,complications,haemorrhagic,ischaemic,outcome,stroke,stroke type,clinical neurology ,/dk/atira/pure/subjectarea/asjc/2700/2728 |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023) Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit Faculty of Medicine and Health Sciences > Research Groups > Health Services and Primary Care Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health Faculty of Medicine and Health Sciences > Research Centres > Population Health |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 24 Jul 2020 23:44 |
| Last Modified: | 19 Oct 2023 02:44 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/76275 |
| DOI: | 10.1007/s13760-020-01416-0 |
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