An analysis of the synthetic tryptamines AMT and 5-MeO-DALT: Emerging 'novel psychoactive drugs'

Arunotayanun, Warunya, Dalley, Jeffrey W., Huang, Xi-Ping, Setola, Vincent, Treble, Ric, Iversen, Leslie, Roth, Bryan L. and Gibbons, Simon (2013) An analysis of the synthetic tryptamines AMT and 5-MeO-DALT: Emerging 'novel psychoactive drugs'. Bioorganic & Medicinal Chemistry Letters, 23 (11). pp. 3411-3415. ISSN 0960-894X

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Abstract

Novel Psychoactive Drugs (NPD) can be sold without restriction and are often synthetic analogues of controlled drugs. The tryptamines are an important class of NPD as they bind to the various serotonin (5-HT) receptor subtypes and cause psychosis and hallucinations that can lead to injury or death through misadventure. Here we report on the structure elucidation and receptor binding profiles of two widely marketed tryptamine-derived NPDs, namely alpha-methyl-tryptamine and 5-methoxy-N,N-diallyl-tryptamine.

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Pharmacy
Depositing User:	LivePure Connector
Date Deposited:	15 Jul 2020 23:38
Last Modified:	04 Mar 2024 17:57
URI:	https://ueaeprints.uea.ac.uk/id/eprint/76095
DOI:	10.1016/j.bmcl.2013.03.066

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