Molecular Similarity of MDR Inhibitors

Zloh, Mire and Gibbons, Simon (2004) Molecular Similarity of MDR Inhibitors. International Journal of Molecular Sciences, 5 (2). pp. 37-47. ISSN 1661-6596

Full text not available from this repository.

Abstract

The molecular similarity of multidrug resistance (MDR) inhibitors was evaluated using the point centred atom charge approach in an attempt to find some common features of structurally unrelated inhibitors. A series of inhibitors of bacterial MDR were studied and there is a high similarity between these in terms of their shape, presence and orientation of aromatic ring moieties. A comparison of the lipophilic properties of these molecules has also been conducted suggesting that this factor is important in MDR inhibition.

Item Type: Article
Faculty \ School: Faculty of Science > School of Pharmacy
Related URLs:
Depositing User: LivePure Connector
Date Deposited: 01 Jul 2020 00:01
Last Modified: 24 Sep 2022 06:05
URI: https://ueaeprints.uea.ac.uk/id/eprint/75854
DOI: 10.3390/i5020037

Actions (login required)

View Item View Item