C15 acetogenins with antistaphylococcal activity from the red alga Laurencia glandulifera

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Kladi, Maria, Vagias, Constantinos, Stavri, Michael, Rahman, M. Mukhlesur, Gibbons, Simon and Roussis, Vassilios (2008) C15 acetogenins with antistaphylococcal activity from the red alga Laurencia glandulifera. Phytochemistry Letters, 1 (1). pp. 31-36. ISSN 1874-3900

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Abstract

Five new C15 eight-membered cyclic ethers (1, 3–6) with a characteristic terminal cis ene–yne moiety, along with the previously reported acetylenic chloro diol (2) were isolated from the organic extract of the red alga Laurencia glandulifera, collected at Crete island in South Greece. Full assignment of all 1H and 13C resonances were carried out by extensive analysis of their NMR spectra. All metabolites were tested for their antistaphylococcal activity and the minimum inhibitory concentrations (MICs) of 2–5 were in the range of 8–256 μg/ml.

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Pharmacy
Related URLs:	https://linkinghub.elsevier.com/retrieve...
Depositing User:	LivePure Connector
Date Deposited:	19 Jun 2020 00:06
Last Modified:	22 Oct 2022 06:20
URI:	https://ueaeprints.uea.ac.uk/id/eprint/75676
DOI:	10.1016/j.phytol.2007.12.004

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