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Angeloni, Cristina, Businaro, Rita and Vauzour, David 
ORCID: https://orcid.org/0000-0001-5952-8756
(2020)
The role of diet in preventing and reducing cognitive decline.
Current Opinion in Psychiatry, 33 (4).
pp. 432-438.
ISSN 0951-7367
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Abstract
Purpose of review: This review summarises the most recent evidence regarding the effects of diet in preventing and reducing age-related cognitive decline and neurodegenerative diseases. Recent findings: Recent evidence indicates that nutraceuticals and whole diet approaches may protect against the development of age-related cognitive decline and pathological neurodegeneration. The neuroprotective effects are diverse depending on the nutrient employed and may involve a reduction of neuroinflammation, an activation of the endogenous antioxidant defence system and a modulation of the gut microbiota structure and function. Summary: This review summarises the existing evidence in favour of diet as a viable alternative approach to directly impact cognitive decline and neurodegenerative diseases. The single nutrient (polyphenols, B vitamins, long-chain polyunsaturated fatty acids) versus whole diet approach (Mediterranean diet, Dietary Approaches to Stop Hypertension, MIND, Nordic, ketogenic) is presented and discussed. Potential mechanisms of action underlying the beneficial effects of these diets are also described. Implementation of large-scale preventive interventions based on dietary patterns identified as being beneficial to brain health should be a research and public health priority, ideally in conjunction with other health-promoting lifestyle factors.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ageing,alzheimer’s disease,brain,dementia,nutrition,sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine Faculty of Medicine and Health Sciences > Research Centres > Norwich Institute for Healthy Aging Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 11 Mar 2020 10:31 |
| Last Modified: | 19 Oct 2023 02:39 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/74475 |
| DOI: | 10.1097/YCO.0000000000000605 |
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