Sheppard, J. P., Tucker, K. L., Davison, W. J., Stevens, R., Aekplakorn, W., Bosworth, H. B., Bove, A., Earle, K., Godwin, M., Green, B. B., Hebert, P., Heneghan, C., Hill, N., Hobbs, F. D. R., Kantola, I., Kerry, S. M., Leiva, A., Magid, D. J., Mant, J., Margolis, K. L., McKinstry, B., McLaughlin, M. A., McNamara, K., Omboni, S., Ogedegbe, O., Parati, G., Varis, J., Verberk, W. J., Wakefield, B. J. and McManus, R. J. (2020) Self-monitoring of blood pressure in patients with hypertension related multi-morbidity: Systematic review and individual patient data meta-analysis. American Journal of Hypertension, 33 (3). 243–251. ISSN 0895-7061
Preview |
PDF (Accepted_Manuscript)
- Accepted Version
Available under License Creative Commons Attribution. Download (1MB) | Preview |
Preview |
PDF (Published_Version)
- Published Version
Available under License Creative Commons Attribution. Download (3MB) | Preview |
Abstract
BACKGROUND: Studies have shown that self-monitoring of blood pressure (BP) is effective when combined with co-interventions, but its efficacy varies in the presence of some co-morbidities. This study examined whether self-monitoring can reduce clinic BP in patients with hypertension-related co-morbidity. METHODS: A systematic review was conducted of articles published in Medline, Embase, and the Cochrane Library up to January 2018. Randomized controlled trials of self-monitoring of BP were selected and individual patient data (IPD) were requested. Contributing studies were prospectively categorized by whether they examined a low/high-intensity co-intervention. Change in BP and likelihood of uncontrolled BP at 12 months were examined according to number and type of hypertension-related co-morbidity in a one-stage IPD meta-analysis. RESULTS: A total of 22 trials were eligible, 16 of which were able to provide IPD for the primary outcome, including 6,522 (89%) participants with follow-up data. Self-monitoring was associated with reduced clinic systolic BP compared to usual care at 12-month follow-up, regardless of the number of hypertension-related co-morbidities (-3.12 mm Hg, [95% confidence intervals -4.78, -1.46 mm Hg]; P value for interaction with number of morbidities = 0.260). Intense interventions were more effective than low-intensity interventions in patients with obesity (P < 0.001 for all outcomes), and possibly stroke (P < 0.004 for BP control outcome only), but this effect was not observed in patients with coronary heart disease, diabetes, or chronic kidney disease. CONCLUSIONS: Self-monitoring lowers BP regardless of the number of hypertension-related co-morbidities, but may only be effective in conditions such obesity or stroke when combined with high-intensity co-interventions.
Item Type: | Article |
---|---|
Uncontrolled Keywords: | clinical inertia,controlled-trial,disease,intervention,management,multimorbidity,prevalence,primary-care,telemedicine,urban,blood pressure,coronary heart disease,diabetes,hypertension,obesity,randomized controlled trial,stroke,sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being |
Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
Related URLs: | |
Depositing User: | LivePure Connector |
Date Deposited: | 03 Dec 2019 02:13 |
Last Modified: | 22 Oct 2022 05:32 |
URI: | https://ueaeprints.uea.ac.uk/id/eprint/73243 |
DOI: | 10.1093/ajh/hpz182 |
Downloads
Downloads per month over past year
Actions (login required)
![]() |
View Item |