Clinical and biological assessment in systemic necrotizing vasculitides

Mukhtyar, C B ORCID: https://orcid.org/0000-0002-9771-6667, Flossmann, O and Luqmani, R A (2006) Clinical and biological assessment in systemic necrotizing vasculitides. Clinical and Experimental Rheumatology, 24 (2 Suppl 41). S92-9. ISSN 0392-856X

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Abstract

The systemic vasculitides are multi-system disorders with significant mortality and morbidity and frequent relapses. Treatment is usually effective but fraught with potentially serious effects. Disease Assessment is important to ensure that patients receive the appropriate treatment. Disease Assessment should comprise measurement of disease activity, chronic irreversible damage and impairment of function. Serological markers can be helpful in assessing disease activity but lack sufficient sensitivity and specificity to be used on their own. Radiological techniques such as Magnetic Resonance Imaging, Ultrasound and Positron Emission Tomography show promise in the large vessel vasculitides but require validation in large studies. Clinical Assessment tools are the current gold standard for the assessment of disease activity, damage and function.

Item Type:	Article
Uncontrolled Keywords:	blood,analysis,biopsy,clinical trials as topic,humans,magnetic resonance imaging,blood,positron-emission tomography,prognosis,radiography,sensitivity and specificity,severity of illness index,ultrasonics,blood
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User:	LivePure Connector
Date Deposited:	27 Nov 2019 02:01
Last Modified:	22 Oct 2022 05:29
URI:	https://ueaeprints.uea.ac.uk/id/eprint/73118
DOI:

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