Chalmers, Rachel M, Davies, Angharad and Tyler, Kevin ORCID: (2019) Cryptosporidium. Microbiology, 165 (5). pp. 500-502. ISSN 1350-0872

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The protozoan Cryptosporidium is notorious for its resistance to chlorine disinfection, a mainstay of water treatment. Human infections, mainly of the small intestine, arise from consumption of faecally contaminated food or water, environmental exposure, and person-to-person or animal-to-person spread. Acute gastrointestinal symptoms can be prolonged but are usually self-limiting. Problems arise with immune-deficient, including malnourished, people including chronic diarrhoea, hepato-biliary tree and extra-gastrointestinal site infection, and few options for treatment or prevention exist. Although genomics has enabled refined classification, identification of chemotherapeutic targets and vaccine candidates, and putative factors for host adaption and pathogenesis, their confirmation has been hampered by a lack of biological tools.

Item Type: Article
Additional Information: Early Title: Cryptosporidium: The protozoan keeping the water industry awake at night
Uncontrolled Keywords: cryptosporidium,infection,sequelae,microbiology,sdg 2 - zero hunger,sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/2400/2404
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology
Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health
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Depositing User: LivePure Connector
Date Deposited: 13 May 2019 15:30
Last Modified: 19 Oct 2023 02:19
DOI: 10.1099/mic.0.000764


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