Chalmers, Rachel M, Davies, Angharad and Tyler, Kevin ORCID: https://orcid.org/0000-0002-0647-8158 (2019) Cryptosporidium. Microbiology, 165 (5). pp. 500-502. ISSN 1350-0872
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Abstract
The protozoan Cryptosporidium is notorious for its resistance to chlorine disinfection, a mainstay of water treatment. Human infections, mainly of the small intestine, arise from consumption of faecally contaminated food or water, environmental exposure, and person-to-person or animal-to-person spread. Acute gastrointestinal symptoms can be prolonged but are usually self-limiting. Problems arise with immune-deficient, including malnourished, people including chronic diarrhoea, hepato-biliary tree and extra-gastrointestinal site infection, and few options for treatment or prevention exist. Although genomics has enabled refined classification, identification of chemotherapeutic targets and vaccine candidates, and putative factors for host adaption and pathogenesis, their confirmation has been hampered by a lack of biological tools.
Item Type: | Article |
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Additional Information: | Early Title: Cryptosporidium: The protozoan keeping the water industry awake at night |
Uncontrolled Keywords: | cryptosporidium,infection,sequelae,microbiology,sdg 2 - zero hunger,sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/2400/2404 |
Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health Faculty of Medicine and Health Sciences > Research Groups > Pathogen Biology Group |
Related URLs: | |
Depositing User: | LivePure Connector |
Date Deposited: | 13 May 2019 15:30 |
Last Modified: | 25 Sep 2024 13:48 |
URI: | https://ueaeprints.uea.ac.uk/id/eprint/70970 |
DOI: | 10.1099/mic.0.000764 |
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