Effect of adenosine on P2X7 receptor-mediated Ca2+ signalling in human Muller cells and retinal neurons

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Sanderson, Julie, Colison, D.J., Eldred, Julie A, Duncan, George and Broadway, David C (2003) Effect of adenosine on P2X7 receptor-mediated Ca2+ signalling in human Muller cells and retinal neurons. Investigative Ophthalmology and Visual Science, 44. p. 5204. ISSN 1552-5783

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Abstract

The P2X7 ATP receptor is proposed to play a role in apoptosis. Functional expression of this receptor in human retinal cells in culture was investigated using the P2X7 agonist BzATP. Adenosine is a proposed neuromodulator in the retina. The effect of adenosine on BzATP-induced Ca2+ signalling was also investigated.

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Biological Sciences Faculty of Science > School of Pharmacy (former - to 2024)
UEA Research Groups:	Faculty of Science > Research Groups > Pharmaceutical Cell Biology (former - to 2017) Faculty of Science > Research Groups > Molecular and Tissue Pharmacology
Related URLs:	https://iovs.arvojournals.org/article.as...
Depositing User:	EPrints Services
Date Deposited:	01 Oct 2010 13:37
Last Modified:	24 Sep 2024 10:13
URI:	https://ueaeprints.uea.ac.uk/id/eprint/696
DOI:

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