Randomised controlled trial of a theory-based behavioural intervention to reduce formula milk intake

Lakshman, Rajalakshmi, Sharp, Stephen J, Whittle, Fiona, Schiff, Annie, Hardeman, Wendy ORCID: https://orcid.org/0000-0002-6498-9407, Irvine, Lisa ORCID: https://orcid.org/0000-0003-1936-3584, Wilson, Ed ORCID: https://orcid.org/0000-0002-8369-1577, Griffin, Simon J and Ong, Ken K (2018) Randomised controlled trial of a theory-based behavioural intervention to reduce formula milk intake. Archives of Disease in Childhood, 103 (11). pp. 1054-1060. ISSN 0003-9888

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Abstract

Objective: To assess the efficacy of a theory-based behavioural intervention to prevent rapidweight gain in formula-milk fed infants.  Design: In this single (assessor) blind, randomised controlled trial, 669 healthy full-terminfants receiving formula-milk within 14 weeks of birth were individually-randomised tointervention (n=340) or attention-matched control (n=329) groups. The intervention aimed toreduce formula-milk intakes, and promote responsive feeding and growth monitoring toprevent rapid weight gain (>+ 0.67 standard deviation scores [SDS]). It was delivered tomothers by trained facilitators up to infant age 6 months through 3 face-to-face contacts, 2telephone contacts, and written materials.  Results: Retention was 93% (622) at 6 months, 88% (586) at 12 months, and 94% attended >4/5 sessions. The intervention strengthened maternal attitudes to following infant feedingrecommendations, reduced reported milk intakes at ages 3 (-14%; intervention vs controlinfants), 4 (-12%), 5 (-9%), and 6 (-7%) months, slowed initial infant weight gain frombaseline to 6 months (mean change 0.32 vs 0.42 SDS, baseline-adjusted difference(intervention vs control) -0.08 [95% CI; -0.17, -0.004] SDS), but had no effect on the primaryoutcome of weight gain to 12 months (baseline-adjusted difference -0.04 [-0.17, 0.10] SDS).By 12 months, 40.3% of infants in the intervention group and 45.9% in the control groupshowed rapid weight gain (OR: 0.84 [95% CI; 0.59, 1.17]).  Conclusions: Despite reducing milk intakes and initial weight gain, the intervention did notalter the high prevalence of rapid weight gain to age 12 months suggesting the need forsustained intervention.

Item Type:	Article
Uncontrolled Keywords:	infant feeding,formula-milk,growth,obesity prevention,rapid weight gain,behavioural intervention,sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Medicine and Health Sciences > School of Health Sciences Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Health Promotion Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023) Faculty of Medicine and Health Sciences > Research Groups > Health Economics Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health Faculty of Medicine and Health Sciences > Research Centres > Population Health
Depositing User:	Pure Connector
Date Deposited:	01 May 2018 11:30
Last Modified:	06 Jun 2024 15:01
URI:	https://ueaeprints.uea.ac.uk/id/eprint/66879
DOI:	10.1136/archdischild-2018-314784

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