Formal total synthesis of (+)-C9-deoxyomuralide from l-leucine using a double sacrificial chirality transfer approach

Bulman Page, Philip C., Goodyear, Ross L., Horton, Alexandra E., Chan, Yohan, Karim, Rehana, O'Connell, Maria A. ORCID: https://orcid.org/0000-0002-0267-0951, Hamilton, Christopher, Slawin, Alexandra M. Z., Buckley, Benjamin R. and Allin, Steven M. (2017) Formal total synthesis of (+)-C9-deoxyomuralide from l-leucine using a double sacrificial chirality transfer approach. The Journal of Organic Chemistry, 82 (23). 12209–12223. ISSN 0022-3263

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Abstract

Formal stereocontrolled syntheses of (±)- and (+)-C9-deoxyomuralide is reported, constituting one of the shortest routes to the full carbon skeleton reported to date.

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Chemistry (former - to 2024) Faculty of Science > School of Pharmacy (former - to 2024)
UEA Research Groups:	Faculty of Science > Research Groups > Chemistry of Materials and Catalysis Faculty of Science > Research Groups > Chemical Biology and Medicinal Chemistry (former - to 2021) Faculty of Science > Research Groups > Molecular and Tissue Pharmacology
Depositing User:	Pure Connector
Date Deposited:	21 Dec 2017 13:49
Last Modified:	25 Sep 2024 13:10
URI:	https://ueaeprints.uea.ac.uk/id/eprint/65799
DOI:	10.1021/acs.joc.7b02078

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