The relationship between the dietary inflammatory index and prevalence of radiographic symptomatic osteoarthritis: Data from the Osteoarthritis Initiative

Veronese, Nicola, Shivappa, Nitin, Stubbs, Brendon, Smith, Toby, Hébert, James, Cooper, Cyrus, Guglielmi, Giuseppe, Reginster, Jean-Yves, Rizzoli, Renè and Maggi, Stefania (2019) The relationship between the dietary inflammatory index and prevalence of radiographic symptomatic osteoarthritis: Data from the Osteoarthritis Initiative. European Journal of Nutrition, 58 (1). 253–260. ISSN 1436-6207

[img]
Preview
PDF (Accepted manuscript) - Submitted Version
Available under License ["licenses_description_unspecified" not defined].

Download (794kB) | Preview

Abstract

Purpose: To investigate whether higher dietary inflammatory index (DII) levels were associated with higher prevalence of radiographic symptomatic knee osteoarthritis in a large cohort of North American people from the Osteoarthritis Initiative database. Methods: 4,358 community-dwelling participants (2527 females; mean age: 61.2 years) from the Osteoarthritis Initiative were identified. DII was calculated using the validated Block Brief 2000 Food-Frequency Questionnaire and categorized into four quartiles. Knee radiographic symptomatic osteoarthritis was diagnosed clinically and radiologically. The strength of association between DII (divided in quartiles) and knee osteoarthritis was investigated through a logistic regression analysis and reported as odds ratios (ORs) with 95% confidence intervals (CIs), adjusted for potential confounders. Results: Participants with a higher DII score, indicating a more pro-inflammatory diet, had a significantly higher prevalence of radiographic symptomatic knee osteoarthritis compared to those with lower DII score (Quartile 4: 35.4% vs. Quartile 1: 24.0%; p<0.0001). Using a logistic regression analysis, adjusting for 11 potential confounders, participants with the highest DII score (Quartile 4) had a significantly higher probability of experiencing radiographic symptomatic knee osteoarthritis (OR: 1.40; 95% CI: 1.14 to 1.72; p=0.002) compared to participants with the lowest DII score (Quartile 1). Conclusions: Higher DII values are associated with higher prevalence of radiographic symptomatic knee osteoarthritis.

Item Type: Article
Uncontrolled Keywords: knee osteoarthritis,dietary inflammatory index,inflammation
Faculty \ School: Faculty of Medicine and Health Sciences > School of Health Sciences
Depositing User: Pure Connector
Date Deposited: 29 Nov 2017 06:07
Last Modified: 18 Mar 2020 00:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/65593
DOI: 10.1007/s00394-017-1589-6

Actions (login required)

View Item View Item