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Veronese, Nicola, Shivappa, Nitin, Stubbs, Brendon, Smith, Toby 
ORCID: https://orcid.org/0000-0003-1673-2954, Hébert, James, Cooper, Cyrus, Guglielmi, Giuseppe, Reginster, Jean-Yves, Rizzoli, Renè and Maggi, Stefania
(2019)
The relationship between the dietary inflammatory index and prevalence of radiographic symptomatic osteoarthritis: Data from the Osteoarthritis Initiative.
European Journal of Nutrition, 58 (1).
253–260.
ISSN 1436-6207
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Abstract
Purpose: To investigate whether higher dietary inflammatory index (DII ® ) scores were associated with higher prevalence of radiographic symptomatic knee osteoarthritis in a large cohort of North American people from the Osteoarthritis Initiative database. Methods: A total of 4358 community-dwelling participants (2527 females; mean age 61.2 years) from the Osteoarthritis Initiative were identified. DII ® scores were calculated using the validated Block Brief 2000 Food-Frequency Questionnaire and scores were categorized into quartiles. Knee radiographic symptomatic osteoarthritis was diagnosed clinically and radiologically. The strength of association between divided into quartiles (DII ® ) and knee osteoarthritis was investigated through a logistic regression analysis, which adjusted for potential confounders, and results were reported as odds ratios (ORs) with 95% confidence intervals (CIs). Results: Participants with a higher DII ® score, indicating a more pro-inflammatory diet, had a significantly higher prevalence of radiographic symptomatic knee osteoarthritis compared to those with lower DII ® score (quartile 4: 35.4% vs. quartile 1: 24.0%; p < 0.0001). Using a logistic regression analysis, adjusting for 11 potential confounders, participants with the highest DII ® score (quartile 4) had a significantly higher probability of experiencing radiographic symptomatic knee osteoarthritis (OR 1.40; 95% CI 1.14–1.72; p = 0.002) compared to participants with the lowest DII ® score (quartile 1). Conclusions: Higher DII ® values are associated with higher prevalence of radiographic symptomatic knee osteoarthritis.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | knee osteoarthritis,dietary inflammatory index,inflammation |
| Faculty \ School: | Faculty of Medicine and Health Sciences > School of Health Sciences |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Rehabilitation Faculty of Medicine and Health Sciences > Research Groups > Health Promotion Faculty of Science > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Centres > Population Health |
| Related URLs: | |
| Depositing User: | Pure Connector |
| Date Deposited: | 29 Nov 2017 06:07 |
| Last Modified: | 19 Oct 2023 02:06 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/65593 |
| DOI: | 10.1007/s00394-017-1589-6 |
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