Illusory sensation of movement induced by repetitive transcranial magnetic stimulation

Christensen, Mark Schram, Lundbye-Jensen, Jesper, Grey, Michael James ORCID: https://orcid.org/0000-0002-3216-3272, Vejlby, Alexandra Damgaard, Belhage, Bo and Nielsen, Jens Bo (2010) Illusory sensation of movement induced by repetitive transcranial magnetic stimulation. PLoS One, 5 (10). ISSN 1932-6203

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Abstract

Human movement sense relies on both somatosensory feedback and on knowledge of the motor commands used to produce the movement. We have induced a movement illusion using repetitive transcranial magnetic stimulation over primary motor cortex and dorsal premotor cortex in the absence of limb movement and its associated somatosensory feedback. Afferent and efferent neural signalling was abolished in the arm with ischemic nerve block, and in the leg with spinal nerve block. Movement sensation was assessed following trains of high-frequency repetitive transcranial magnetic stimulation applied over primary motor cortex, dorsal premotor cortex, and a control area (posterior parietal cortex). Magnetic stimulation over primary motor cortex and dorsal premotor cortex produced a movement sensation that was significantly greater than stimulation over the control region. Movement sensation after dorsal premotor cortex stimulation was less affected by sensory and motor deprivation than was primary motor cortex stimulation. We propose that repetitive transcranial magnetic stimulation over dorsal premotor cortex produces a corollary discharge that is perceived as movement.

Item Type:	Article
Faculty \ School:	Faculty of Medicine and Health Sciences > School of Health Sciences
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Rehabilitation
Related URLs:	http://journals.plos.org/plosone/article...
Depositing User:	Pure Connector
Date Deposited:	27 Jun 2017 05:06
Last Modified:	31 Jan 2024 02:15
URI:	https://ueaeprints.uea.ac.uk/id/eprint/63856
DOI:	10.1371/journal.pone.0013301

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