An unusual but reversible cause of ventricular fibrillation

Merinopoulos, I., Vassiliou, V. ORCID: https://orcid.org/0000-0002-4005-7752, Porter, J. N., Acton, S. and Braganza, D. R. (2013) An unusual but reversible cause of ventricular fibrillation. Journal of the Royal College of Physicians of Edinburgh, 43 (2). pp. 119-121. ISSN 1478-2715

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Abstract

A 61-year-old woman was admitted with general malaise, chest pain and breathlessness. During her inpatient stay she sustained a ventricular fibrillation (VF) arrest which was successfully terminated with direct current cardioversion. Cardiac investigations revealed poor left ventricular systolic function but unequivocally normal coronary arteries. During the course of her admission a macular rash developed and following investigations including a renal biopsy, a new diagnosis of systemic lupus erythematosus (SLE) and related myocarditis was reached. First presentation of lupus with myocarditis and VF is uncommon, however reaching the correct diagnosis is important as due to the reversible nature of the condition and improvement in left ventricular systolic function with medical therapy, an implantable cardioverter defibrillator (ICD) might not be appropriate. Our case report demonstrates the importance of screening for reversible conditions when considering ICD therapy for secondary prevention of malignant arrhythmias.

Item Type: Article
Uncontrolled Keywords: lupus,sle,myocarditis,ventricular fibrillation,cardiac arrest
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Science > Research Groups > Norwich Epidemiology Centre
Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre
Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health
Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health
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Depositing User: Pure Connector
Date Deposited: 23 Jun 2017 05:06
Last Modified: 31 Jan 2024 02:15
URI: https://ueaeprints.uea.ac.uk/id/eprint/63818
DOI: 10.4997/JRCPE.2013.206

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