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Grenga, Lucia, Little, Richard H and Malone, Jacob G 
ORCID: https://orcid.org/0000-0003-1959-6820
(2017)
Quick change: post-transcriptional regulation in Pseudomonas.
FEMS Microbiology Letters, 364 (14).
ISSN 0378-1097
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Abstract
Pseudomonas species have evolved dynamic and intricate regulatory networks to fine-tune gene expression, with complex regulation occurring at every stage in the processing of genetic information. This approach enables Pseudomonas to generate precise individual responses to the environment in order to improve their fitness and resource economy. The weak correlations we observe between RNA and protein abundance highlight the significant regulatory contribution of a series of intersecting post-transcriptional pathways, influencing mRNA stability, translational activity and ribosome function, to Pseudomonas environmental responses. This review examines our current understanding of three major post-transcriptional regulatory systems in Pseudomonas spp.; Gac/Rsm, Hfq and RimK, and presents an overview of new research frontiers, emerging genome-wide methodologies, and their potential for the study of global regulatory responses in Pseudomonas.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | translational control,pseudomonas,post-transcriptional regulation,regulatory responses,signalling pathway,ribosomal modification |
| Faculty \ School: | Faculty of Science > School of Biological Sciences |
| UEA Research Groups: | Faculty of Science > Research Groups > Molecular Microbiology |
| Related URLs: | |
| Depositing User: | Pure Connector |
| Date Deposited: | 20 Jun 2017 05:05 |
| Last Modified: | 23 Oct 2024 23:47 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/63773 |
| DOI: | 10.1093/femsle/fnx125 |
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