Health utility reporting in Chronic Rhinosinusitis patients

Bewick, Jessica, Morris, Steve, Hopkins, Claire, Erskine, Sally and Philpott, Carl ORCID: https://orcid.org/0000-0002-1125-3236 (2018) Health utility reporting in Chronic Rhinosinusitis patients. Clinical Otolaryngology, 43 (1). 90–95. ISSN 1749-4478

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Abstract

Objectives: Direct comparison of different diseases allows clinicians and researchers to place the burden of symptoms and impact on quality of life of each condition in context. Generic health-related quality of life assessment tools allow such analysis, limited data is available for British patients with Chronic rhinosinusitis. Design: As part of a larger feasibility study, patients underwent baseline assessment using the SNOT-22, SF-12 and EQ-5D-5L tools. Data was analysed using Microsoft excel and algorithms available for the analysis of the later 2 tools. We plotted EQ-5D-5L VAS and utility scores and SF-12 MCS and PCS scores separately against SNOT-22 scores and quantified associations using bivariate ordinary least squares regression analysis. Setting: Patients were prospectively recruited from 6 UK outpatient clinics. Participants: Adult patients with chronic rhinosinusitis without nasal polyps (CRSsNPs). Main Outcome measures: Baseline SNOT-22, SF-12 and EQ-5D-5L scores. Results: Fifty-two adults were recruited with a mean age of 55 years, 51% were male. The mean SNOT-22 score was 43.82. Mental and physical component scores of the SF-12 were 46.53 and 46 respectively. Mean index score computed form the EQ-5D-5L was 0.75. Worse (higher) SNOT-22 scores were associated with lower EQ-5D-5L VAS and utility scores and SF-12 MCS and PCS scores. Conclusion: The EQ-5D-5L suggests that British CRSsNPs patients are negatively impacted with regards to quality of life. We found the SF-12 to be less sensitive and conclude that the EQ-5D-5L tool is a quick and accessible method for assessing QOL in order it can be compared with other disease states.

Item Type:	Article
Uncontrolled Keywords:	rhinitis,endoscopic sinus surgery ,rhino-sinusitis and complications
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit Faculty of Medicine and Health Sciences > Research Groups > Respiratory and Airways Group Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
Depositing User:	Pure Connector
Date Deposited:	09 May 2017 05:09
Last Modified:	19 Oct 2023 01:59
URI:	https://ueaeprints.uea.ac.uk/id/eprint/63413
DOI:	10.1111/coa.12903

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