The role of myocardial fibrosis in determining the success rate of ablation for the treatment of atrial fibrillation

Selvendran, Subothini, Aggarwal, Nikhil, Li, Justin, Tse, Gary and Vassiliou, Vassilios S. ORCID: https://orcid.org/0000-0002-4005-7752 (2017) The role of myocardial fibrosis in determining the success rate of ablation for the treatment of atrial fibrillation. Minerva Cardioangiologica, 65 (4). pp. 420-426. ISSN 0026-4725

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Abstract

Atrial fibrillation is the most common sustained cardiac arrhythmia and with an aging population its prevalence will increase. In addition to appropriate anticoagulation to reduce the thromboembolic risk, there has been an increasing need for a personalised approach in identifying which patients are likely to benefit more from atrial fibrillation ablation procedures. This review will discuss the role of myocardial fibrosis in patients with atrial fibrillation, its mechanistic role, association with biomarkers and how this could potentially be of use in the development of a risk score identifying the success of maintaining sinus rhythm following an electrophysiological ablation.

Item Type: Article
Uncontrolled Keywords: atrial fibrillation,ablation,myocardial fibrosis
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health
Faculty of Science > Research Groups > Norwich Epidemiology Centre
Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre
Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health
Depositing User: Pure Connector
Date Deposited: 06 Apr 2017 06:59
Last Modified: 19 Oct 2023 01:56
URI: https://ueaeprints.uea.ac.uk/id/eprint/63171
DOI: 10.23736/S0026-4725.17.04371-7

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