Synthesis and photophysical properties of iron-carbonyl complex-coumarin conjugates as potential bimodal IR-fluorescent probes

Glowacka, Paulina C., Maindron, Nicolas, Stephenson, G. Richard, Romieu, Anthony, Renard, Pierre-Yves and Emery, Flavio da Silva (2016) Synthesis and photophysical properties of iron-carbonyl complex-coumarin conjugates as potential bimodal IR-fluorescent probes. Tetrahedron Letters, 57 (45). 4991–4996. ISSN 0040-4039

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Abstract

An expedient synthesis of the first examples of iron-carbonyl complex-coumarin conjugates is reported. 7-Amino/7-hydroxycoumarin derivatives have been readily derivatized through an easily implemented single-step reaction involving the tricarbonyl(η5-cyclohexadienyl)iron(1+) cation [(C6H7)Fe(CO)3]+. The scope and limitations of this N-/O-alkylation reaction were also investigated. The fluorescence properties of these novel metal-carbonyl complexes have been studied and support their further use as valuable building blocks in the design of bimodal contrast agents for combined vibrational and fluorescence imaging.

Item Type: Article
Uncontrolled Keywords: coumarins,dual imaging probes,fluorescence,infrared,iron-carbonyl complexes
Faculty \ School: Faculty of Science > School of Chemistry
Related URLs:
Depositing User: Pure Connector
Date Deposited: 05 Oct 2016 16:00
Last Modified: 17 Mar 2020 22:27
URI: https://ueaeprints.uea.ac.uk/id/eprint/60759
DOI: 10.1016/j.tetlet.2016.09.091

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