Calixsugars: Finally Reaching Their Therapeutic Potential?

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Matthews, Susan E. ORCID: https://orcid.org/0000-0001-8821-0851 (2016) Calixsugars: Finally Reaching Their Therapeutic Potential? In: Calixarenes and Beyond. Springer, pp. 559-600. ISBN 978-3-319-31865-3

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Abstract

The synthesis and properties of members of the calixarene family functionalised with carbohydrates have been extensively investigated for the past 20 years. These calixsugars show great potential for applications in the fields of medicinal chemistry, drug and gene delivery, through their ability to bind to lectins and to inhibit enzymes. In this chapter, the current therapeutic status of calixsugars for a range of diseases is discussed, including in vivo evaluation. Applications in bacterial infections and cancer are covered, in addition to recent developments in their use as carrier molecules and vectors in gene therapy.

Item Type:	Book Section
Uncontrolled Keywords:	sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Science > School of Pharmacy Faculty of Science > School of Natural Sciences
UEA Research Groups:	Faculty of Science > Research Groups > Medicinal Chemistry (former - to 2017) Faculty of Science > Research Groups > Chemical Biology and Medicinal Chemistry (former - to 2021)
Related URLs:	http://link.springer.com/10.1007/978-3-3... http://link.springer.com/10.1007/978-3-3...
Depositing User:	Pure Connector
Date Deposited:	24 Sep 2016 01:02
Last Modified:	04 May 2024 00:20
URI:	https://ueaeprints.uea.ac.uk/id/eprint/60401
DOI:	10.1007/978-3-319-31867-7_22

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