Can Nutritional Intervention Counteract Immunosenescence in the Elderly?

Clements, Sarah J. and Carding, Simon R. (2016) Can Nutritional Intervention Counteract Immunosenescence in the Elderly? In: Molecular Basis of Nutrition and Aging: A Volume in the Molecular Nutrition Series. Elsevier, pp. 375-391. ISBN 9780128018279

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Abstract

Immunosenescence, the progressive decline in immune function with increasing age, is a predominant problem within the current aging population and is associated with poor response to vaccinations and increasing levels of infection, as well as diseases including cardiovascular disease and cancer. The changes to the immune system observed with aging may not be permanent and there is evidence of nutritional interventions promoting beneficial changes to immune cells. The impact of fatty acids is a key example, where evidence suggests that recommended intakes should be tailored specifically for the elderly and highlights the importance of the type fat within the diet. New studies are beginning to focus on the more relevant whole diet rather than single or combinations of nutrients with emerging evidence of the Mediterranean and Okinawa diets being associated with longevity and reduction in inflammation, with the potential for immunomodulation.

Item Type:	Book Section
Uncontrolled Keywords:	aging,immune system,immunosenescence,nutrition,sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology
Depositing User:	Pure Connector
Date Deposited:	24 Sep 2016 01:01
Last Modified:	21 Oct 2022 23:54
URI:	https://ueaeprints.uea.ac.uk/id/eprint/60360
DOI:	10.1016/B978-0-12-801816-3.00028-5

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