Thiol redox and pKa properties of mycothiol, the predomiant low molecular weight thiol cofactor in the Actinomycetes

Sharma, Sunil V, Van Laer, Koen, Messens, Joris and Hamilton, Chris James (2016) Thiol redox and pKa properties of mycothiol, the predomiant low molecular weight thiol cofactor in the Actinomycetes. ChemBioChem, 17 (18). 1689–1692. ISSN 1439-4227

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Abstract

Herein, the thiol pKa and standard redox potential of mycothiol, the major low molecular weight thiol cofactor in the actinomycetes, are reported. The measured standard redox potential reveals substantial discrepancies in one or more of the other previously measured intracellular parameters that are relevant to mycothiol redox biochemistry.

Item Type:	Article
Uncontrolled Keywords:	mycothiol,redox potential,thiol pka
Faculty \ School:	Faculty of Science > School of Pharmacy (former - to 2024)
UEA Research Groups:	Faculty of Science > Research Groups > Chemical Biology and Medicinal Chemistry (former - to 2021)
Depositing User:	Pure Connector
Date Deposited:	01 Jul 2016 14:00
Last Modified:	13 Dec 2024 01:23
URI:	https://ueaeprints.uea.ac.uk/id/eprint/59644
DOI:	10.1002/cbic.201600228

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