Constructing Phylogenetic Networks based on Trinets

Oldman, James (2015) Constructing Phylogenetic Networks based on Trinets. Doctoral thesis, University of East Anglia.

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Abstract

Abstract
The motivation of phylogenetic analysis is to discover the evolutionary
relationships between species, with the broader aim of understanding
the origins of life. Our understanding of the molecular character-
istics of species through DNA sequencing permanently changed the
approach to understanding the evolution of species. Indeed, the ad-
vancement of technology has played a major role in the fast sequencing
of DNA as well as the use of computers in solving biological problems
in general. These evolutionary relationships are often visualised and
represented using a phylogenetic tree. As a natural generalisation of
phylogenetic trees, phylogenetic networks are used in biology to rep-
resent evolutionary histories that contain reticulate, or non-treelike
events such as recombination, hybridisation and horizontal gene trans-
fer. The reconstruction of explicit phylogenetic networks from biolog-
ical data is currently an active area of phylogenetics research. Here
we consider the problem of constructing such networks from trinets,
that is, phylogenetic networks on three leaves. More speci�cally, we
present the SeqTrinet and TriLoNet methods, which form a supernet-
work based approach to constructing level-1 phylogenetic networks
directly from multiple sequence alignments.

Item Type: Thesis (Doctoral)
Faculty \ School: Faculty of Science > School of Computing Sciences
Depositing User: Vailele Chittock
Date Deposited: 22 Jun 2016 08:44
Last Modified: 30 Sep 2016 00:38
URI: https://ueaeprints.uea.ac.uk/id/eprint/59446
DOI:

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