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ToolsBeadsworth, Michael, Beeley, Alex, Roberts, Paul, Farragher, Brian, Watson, Alastair and Beeching, Nick (2014) Clostridium difficile toxin in adult inpatients in an urban hospital in Malawi: Associations with HIV status, CD4 count and diarrhoea. International Journal of Tropical Medicine, 9 (1). pp. 7-9. ISSN 1818-779X
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Abstract
Clostridium difficile Infection (CDI) is the cause of substantial morbidity and mortality in the developed world. However, very little is known about the burden of CDI in sub-Saharan Africa where less antibiotic restriction, high HIV prevalence and greater impact from nosocomial infection mean the potential for a significant disease burden is great. Researchers investigated the prevalence of Clostridium difficile Toxin (CDT), assessing association with HIV, CD4 count and diarrhoea in medical in-patients in Malawi. In 206 patients tested for CDT, 28 (13.6%) were positive. No significant associations were seen with either diarrhoea or HIV. There was a non-statistically significant (p = 0.056) association between CD4 counts of <50 and CDT. The frequency and the clinical implications of CDI in both HIV positive and negative patients in sub-Saharan Africa, requires further assessment.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology |
| Related URLs: | |
| Depositing User: | Pure Connector |
| Date Deposited: | 01 Apr 2016 10:10 |
| Last Modified: | 06 Feb 2025 06:14 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/58032 |
| DOI: | 10.3923/ijtmed.2014.7.9 |
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