Factors determining the risk of diabetes foot amputations - a retrospective analysis of a tertiary diabetes foot care service

Beaney, A.J., Nunney, I., Gooday, C. and Dhatariya, K. (2016) Factors determining the risk of diabetes foot amputations - a retrospective analysis of a tertiary diabetes foot care service. Diabetes Research and Clinical Practice, 114. pp. 69-74. ISSN 0168-8227

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Abstract

Aims: To identify which factors predict the need for minor or major amputation in patients attending a multidisciplinary diabetic foot clinic. Methods: A retrospective analysis of patients who attended over a 27 month period were included. Patients had to have attended ≥3 consecutive consultant led clinic appointments within 6 months. Data was collected on HbA1c, clinic attendance, blood pressure, peripheral arterial disease (PAD), and co-morbidities. Patients were followed up for 1 year. Results: 165 patients met the inclusion criteria. 121 were male. 33 patients had amputations. There was an association between poor glycaemic control at baseline and risk of amputation when adjusted for other factors, with those patients having HbA1c ≤58 at less risk of amputation with an odds of 0.14 (0.04 to 0.53) of amputation(p = 0.0036). Other statistically significant factors predictive of amputation were: missing clinic appointments (p = 0.0079); a high Charlson index (p = 0.03314); hypertension (p = 0.0216). No previous revascularisation was protective against amputation (p = 0.0035). However PAD was not seen to be statistically significant, although our results indicated a lower risk of amputation with no PAD. Overall, 34.9% (n = 58) of patients had good glycaemic control (HbA1c <58 mmol/mol) at baseline & 81.3% (n = 135) had improved their glycaemic control at their last follow up appointment. Conclusions: In this cohort poor glycaemic control, poor attendance, previous revascularisation & hypertension were associated with higher risk of amputation, with PAD showing a trend. Moreover, we demonstrated benefits in glycaemic control achieved by attending this DFC, which is likely to translate to longer term diabetes related health benefits.

Item Type:	Article
Uncontrolled Keywords:	diabetic foot,amputation,risk,clinic attendance,hypertension,co-morbidities,sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine
Depositing User:	Pure Connector
Date Deposited:	18 Mar 2016 14:00
Last Modified:	12 Jun 2023 12:40
URI:	https://ueaeprints.uea.ac.uk/id/eprint/57585
DOI:	10.1016/j.diabres.2016.02.001

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