Investigation of a unified strategy for the synthesis of anatoxin analogues: Scope and limitations

Roe, Stephen J., Hughes, David L., Aggarwal, Pooja and Stockman, Robert A. (2009) Investigation of a unified strategy for the synthesis of anatoxin analogues: Scope and limitations. Synthesis, 2009 (22). pp. 3775-3784. ISSN 0039-7881

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Abstract

Syntheses of the potent neurotoxins and biochemical probes anatoxin-a and homoanatoxin and several analogues by a combined two-directional synthesis-tandem reaction strategy are presented. Key steps include an oxidative desymmetrisation and a tandem Michael-intramolecular Mannich cyclisation.

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Chemistry
Depositing User:	Pure Connector
Date Deposited:	11 Jan 2016 16:01
Last Modified:	05 Jan 2023 16:31
URI:	https://ueaeprints.uea.ac.uk/id/eprint/56203
DOI:	10.1055/s-0029-1217021

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