The DynDom3D webserver for the analysis of domain movements in multimeric proteins

Girdlestone, Christopher and Hayward, Steven ORCID: https://orcid.org/0000-0001-6959-2604 (2015) The DynDom3D webserver for the analysis of domain movements in multimeric proteins. Journal of Computational Biology, 23 (1). pp. 21-26. ISSN 1557-8666

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Abstract

DynDom3D is a program for the analysis of domain movements in multimeric proteins. Its input is two structure files that indicate a possible domain movement, but the onus has been on the user to process the files so that there is the necessary one-to-one equivalence between atoms in the two atom lists. This is often a prohibitive task to carry out manually which has limited the application of DynDom3D. Here we report on a webserver with a pre-processor that automatically creates an equivalence between atoms using sequence alignment methods. The processed structure files are passed to DynDom3D and the results are presented on a webpage that includes molecular graphics for easy visualization. The website can be found at: http://www.cmp.uea.ac.uk/dyndom/3D

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Computing Sciences Faculty of Science
UEA Research Groups:	Faculty of Science > Research Groups > Computational Biology
Depositing User:	Pure Connector
Date Deposited:	06 Jan 2016 12:02
Last Modified:	19 Apr 2023 00:54
URI:	https://ueaeprints.uea.ac.uk/id/eprint/56065
DOI:	10.1089/cmb.2015.0143

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