The DynDom3D webserver for the analysis of domain movements in multimeric proteins

Girdlestone, Christopher and Hayward, Steven (2015) The DynDom3D webserver for the analysis of domain movements in multimeric proteins. Journal of Computational Biology, 23 (1). pp. 21-26. ISSN 1557-8666

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Abstract

DynDom3D is a program for the analysis of domain movements in multimeric proteins. Its input is two structure files that indicate a possible domain movement, but the onus has been on the user to process the files so that there is the necessary one-to-one equivalence between atoms in the two atom lists. This is often a prohibitive task to carry out manually which has limited the application of DynDom3D. Here we report on a webserver with a pre-processor that automatically creates an equivalence between atoms using sequence alignment methods. The processed structure files are passed to DynDom3D and the results are presented on a webpage that includes molecular graphics for easy visualization. The website can be found at: http://www.cmp.uea.ac.uk/dyndom/3D

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Computing Sciences Faculty of Science
UEA Research Groups:	Faculty of Science > Research Groups > Computational Biology
Depositing User:	Pure Connector
Date Deposited:	06 Jan 2016 12:02
Last Modified:	06 Feb 2025 05:54
URI:	https://ueaeprints.uea.ac.uk/id/eprint/56065
DOI:	10.1089/cmb.2015.0143

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