Direct health costs of inflammatory polyarthritis 10 years after disease onset: Results from the Norfolk Arthritis Register

Nikiphorou, Elena, Davies, Charlotte, Mugford, Miranda, Cooper, Nicola, Brooksby, Alan, Bunn, Diane, Verstappen, Suzanne M M, Young, Adam, Symmons, Deborah P.M. and Macgregor, Alexander ORCID: https://orcid.org/0000-0003-2163-2325 (2015) Direct health costs of inflammatory polyarthritis 10 years after disease onset: Results from the Norfolk Arthritis Register. Journal of Rheumatology, 42 (5). pp. 794-798. ISSN 0315-162X

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Abstract

Objectives: To explore the change in direct medical costs associated with inflammatory polyarthritis (IP) 10 to 15 years after its onset. Methods: Patients from the Norfolk Arthritis Register who had previously participated in a health economic study in 1999 were traced 10 years later and invited to participate in a further prospective questionnaire-based study. The study was designed to identify direct medical costs and changes in health status over a 6-month period using previously validated questionnaires as the primary source of data. Results: A representative sample of 101 patients with IP from the 1999 cohort provided complete data over the 6-month period. The mean disease duration was 14 years (SD 2.1, median 13.6, interquartile range 12.6–15.4). The mean direct medical cost per patient over the 6-month period was £1496 for IP (inflated for 2013 prices). This compared with £582 (95% CI £355–£964) inflated to 2013 prices per patient with IP 10 years earlier in their disease. The increased cost was largely associated with the use of biologics in the rheumatoid arthritis subgroup of patients (51% of total costs incurred). Other direct cost components included primary care costs (11%), hospital outpatient (19%), day care (12%), and inpatient stay (4%). Conclusion: The direct healthcare costs associated with IP have more than doubled with increasing disease duration, largely as a result of the use of biologics. The results showed a shift in the direct health costs from inpatient to outpatient service use.

Item Type:	Article
Uncontrolled Keywords:	adult,aged,antirheumatic agents,arthritis, rheumatoid,biological products,england,female,health care costs,health status,humans,male,middle aged,registries
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Health Economics Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health Faculty of Medicine and Health Sciences > Research Groups > Musculoskeletal Medicine Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine Faculty of Social Sciences > Research Centres > Centre for Competition Policy Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023) Faculty of Medicine and Health Sciences > Research Groups > Health Promotion Faculty of Science > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre Faculty of Social Sciences > Research Centres > Water Security Research Centre Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
Depositing User:	Pure Connector
Date Deposited:	13 Nov 2015 11:00
Last Modified:	19 Oct 2023 01:26
URI:	https://ueaeprints.uea.ac.uk/id/eprint/55160
DOI:	10.3899/jrheum.140528

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