Magnetic resonance imaging of the optic nerve in optic neuritis

Miller, D. H., Newton, M. R., van der Poel, J. C., du Boulay, E. P., Halliday, A. M., Kendall, B. E., Johnson, G., MacManus, D. G., Moseley, I. F. and McDonald, W. I. (1988) Magnetic resonance imaging of the optic nerve in optic neuritis. Neurology, 38 (2). pp. 175-179. ISSN 0028-3878

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Abstract

Magnetic resonance imaging (MRI) of the optic nerves using the STIR (short inversion time inversion recovery) sequence was performed in 37 adult patients with a recent or past attack of optic neuritis. MRI revealed high-signal regions in 84% of symptomatic and 20% of asymptomatic nerves. The mean longitudinal extent of lesions was 1 cm. Slow or poor visual recovery was associated with more extensive lesions, or lesions within the optic canal. Disk swelling was usually associated with anterior lesions but also occurred with lesions in the canal. Visual evoked potentials were even more sensitive than MRI in detecting lesions and are still the investigation of choice in suspected demyelinating disease involving the optic nerve.

Item Type:	Article
Uncontrolled Keywords:	adult,female,humans,magnetic resonance imaging,male,optic nerve,pathology,optic neuritis,diagnosis
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit Faculty of Medicine and Health Sciences > Research Groups > Cancer Studies
Depositing User:	Pure Connector
Date Deposited:	07 Oct 2015 15:00
Last Modified:	21 Oct 2022 01:19
URI:	https://ueaeprints.uea.ac.uk/id/eprint/54608
DOI:	10.1212/WNL.38.2.175

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